
Experiences on rheumatoid arthritis
More than 400,000 people in Italy suffer from Rheumatoid
Arthritis (RA). It is widespread worldwide with an incidence of 0.4-1%
in the general population.
No climate, racial or employment factors can be demonstrated
to enhance or predispose to the disease.
The disease affects mostly women, with a 5:1 female/male
ratio and a maximum incidence peak in the age group between 25 and 50
years; however, it can occur also in the elderly, teenagers and children.
In Italy, RA has anincidence of approx. 0.6 cases per 1000 people in 1
year.
What is Rheumatoid Arthritis?
RA is a chronic inflammatory disease affecting joints; it
often has a progressive course and may evolve to ankylosis with disabling
deformities; it may affect other organs and systems, such as the eye,
skin and lungs. The onset and course vary considerably, with acute and
rapidly progressive forms or with chronic and slow-developing forms.
The effects of the disease
In RA, the synovial tissue of joints and tendons becomes
the site of a chronic inflammatory process and these structures therefore
appear swollen and become painful, both at rest and with movement, while
the surrounding skin is warm and red. If the inflammatory event persists
for months or years, permanent damage to tendons and joints occurs. In
the initial stages of the inflammatory process, the joints are swollen,
painful and stiff, but maintain their normal functioning, whereas in the
end stage, ankylosis occurs, i.e. the nearly complete fusion of bone heads
with erosion of the joint and loss of its function.
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Pathogenesis
The actual cause of RA is still unknown, but the most accepted
theory suggests that the disease develops when a triggering antigen, still
unknown, comes into contact with an individual that is genetically predisposed
to develop the disease. The consequence of this contact is the activation
of the immune system, which through a complex series of (biochemical and
cellular) events would lead to the development of an acute, then chronic
inflammatory process. Once the immune system has been activated, the normal
immune defences are altered, so that the inflammatory process is self-perpetuated
because the antibodies and the immune cells, which normally act against
foreign and infective agents, attack instead the joint structures.
Symptoms and clinical signs
At onset, pain, swelling and morning stiffness of the affected
joints may appear, as well as signs of general malaise. The onset may
sometimes be acute and sudden, with serious impairment of the general
condition.
Progression may be slow, and occur over a few years during
which the patient suffers from functional limitations, or it may be rapid
and massive, leading to complete disability within a short time.
Local complications are compression neuropathies and tendonitis.
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Therapy
In the light of the above, the basic objectives of the therapy
are:
- Pain reduction
- Reduction of joint stiffness
- Reduction of inflamation and systemic effects
- Control of the disease progress
The treatment with algonix by medilab is centred around
these basic objectives.
Three patients (2 women and 1 man) suffering from RA which
mainly compromised hands and wrists in a symmetrical way, were treated.
Their presenting disease ranged in seriousness between “initial
RA” and “progressive RA”, with a functionality classification
“II stage – preserved ability”.
A course of ten applications to both hands and wrists was
performed.
Selected program: Hyperucemic Arthralgia
The application is performed by stimulating for a maximum
of three courses the joints of the wrist and of each single finger. The
estimated application time for each hand is approx. 15/20 minutes.
In the three cases, there was immediate pain reduction,
resolution of joint stiffness and therefore of joint oedema, and recovery
of the skin colour.
Patients undergo one application per month to maintain the
results achieved.
At present, it is not possible to know whether algonix by
medilab functions exclusively as a symptomatic therapy or whether, through
unknown mechanisms of action, it can significantly modify the clinical
and biological
manifestations of the disease.
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